Low serum total nitrite and nitrate levels in severe leptospirosis
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منابع مشابه
Low serum total nitrite and nitrate levels in severe leptospirosis
BACKGROUND The relationship between inducible nitric oxide synthatase activity and disease severity in leptospirosis is unclear. Nitric oxide is converted to nitrites and nitrates, thus nitrite and nitrate levels (NOx) in serum are considered surrogate markers for nitric oxide. NOx are excreted through the kidneys, and elimination is diminished in renal impairment. We assessed the correlation o...
متن کاملTitle : Low serum total nitrite and nitrate levels in severe leptospirosis
Title: Low serum total nitrite and nitrate levels in severe leptospirosis Authors Thilini Kalugalage, Institute of Biochemistry, Molecular Biology and Biotechnology, University of Colombo, Colombo, Sri Lanka. Email: [email protected] Chaturaka Rodrigo, Department of Clinical Medicine, Faculty of Medicine, University of Colombo, Colombo, Sri Lanka. Email: [email protected] Thamal ...
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Abstract Background and objectives: Smokers are exposed to significant quantities of ROS (Reactive Oxygen Species) and The Level of Nitric Oxide (NO), the primary vasodilator produced by endothelial cells, is changed by cigarette smoking. Cigarette smoking is associated with impaired endothelium-dependent vasodilatation and cardiovascular disease (CVD). The aim of this study is to determine the...
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Background: The assessment of altered nitric oxide (NO) availability is of potentially important diagnostic and prognostic significance. The present study is aimed to investigate the effect of L-arginine (as a natural NO donor) supplementation on NO metabolite in a rabbit model of hypercholesterolemia to find a reliable marker for endothelial NO production. Methods: White male rabbits (n = 30)...
متن کاملHigh serum nitric oxide levels in patients with severe leptospirosis.
Leptospirosis is a globally distributed zoonosis of major public health importance and is associated with severe disease manifestations such as acute renal failure and pulmonary haemorrhage syndrome. However, the extent to which the pathogenesis of leptospirosis mimics sepsis caused by Gram-negative bacteria remains unknown. The aim of this study was to evaluate serum levels of nitric oxide (NO...
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ژورنال
عنوان ژورنال: BMC Infectious Diseases
سال: 2013
ISSN: 1471-2334
DOI: 10.1186/1471-2334-13-206